The CHIASMA Project will devise and demonstrate a comprehensive set of New Approach Methodologies (NAMs) and integrate them in a user friendly, reliable and robust framework to perform human and environmental safety evaluation in a regulatory context. The CHIASMA Project is fully aligned with the EU strategies for the development of the Safe and Sustainable by Design (SSbD) framework to ensure safety and sustainability of enabling and emerging technologies - including those based on chemicals and materials, as addressed in the EU's Chemical Strategy for Sustainability (2020), in the European Green Deal (2021) and in the Advanced Materials 2030 Initiative (AMI2030).

Services

Iron Carbide NPs
Atomistic Descriptor-Driven Cell Viability Prediction for Iron Carbide Nanoparticles (ICNPs)

This web tool hosts a random forest model that predicts cells' survival percentage after 24-hour exposure to Iron Carbide nanoparticles, based on atomistic-level properties.

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SimpleBox4Planet
SimpleBox4Planet

The SimpleBox4Planet tool provides a user-friendly environment to access the SimpleBox, a multimedia mass balance model used to evaluate the fate of chemical substances in the environment. The tool includes a database with the properties of candidate substances used as PFAS alternatives.

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CeresAI-nano
CeresAI-nano

This web-app hosts a validated XGBoost model for the prediction of plant length response class under nanoparticle exposure.

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EffectFactorCalc
EffectFactorCalc

A web application developed for effect factor (EF) calculations using species sensitivity distributions (SSDs) based on chronic and acute toxicity data from freshwater, marine and terrestrial species.

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EU Flag

This project has received funding from the European Union's Horizon Europe Research and Innovation programme under grant agreement nº 101137613.

More information at: chiasma-project.eu