PBFTPK models

Τhe models are based on the work:
P. Chryssafidis, A.A. Tsekouras, P. Macheras, Re-writing Oral Pharmacokinetics Using Physiologically Based Finite Time Pharmacokinetic (PBFTPK) Models, Pharmaceutical Research (2022) 39:691–701. [Link]

Short description of Physiologically based finite time pharmacokinetic (PBFTPK) models

For drugs following linear disposition kinetics, the term p-PBFTPK-m is used, where p is the number of the successive input rates (p = 1, 2, 3, 4) and m the number of the compartments (m = 1,2) F is the bioavailable fraction of dose D, Vd is the volume of distribution and ka, kel are the absorption and elimination first-order rate constants, respectively.